5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- CAS NO.：157066-76-7
- Empirical Formula: C36H40N4O5
- Molecular Weight: 608.73
- MDL number: MFCD09971074
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
![5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE Structural](https://img.chemicalbook.in/CAS/GIF/157066-76-7.gif)
What is 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE?
The Uses of 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
SNAP 5089 is an a1c adrenergic receptor antagonist.
What are the applications of Application
SNAP 5089 is a selective and potent α1A-adrenoreceptor antagonist
Biological Activity
Subtype-selective α 1A -adrenoceptor antagonist that displays > 600-fold selectivity over other adrenoceptors (K i values are 0.35, 220, 370, 540, 800 and 1200 nM for α 1A , α 1B , α 2C , α 1D , α 2B and α 2A subtypes respectively and 540 nM for L-type Ca 2+ channels). Inhibits noradrenalin-induced contractions in rabbit vascular and lower urinary tissues.
Properties of 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
| Boiling point: | 780.3±60.0 °C(Predicted) |
| Density | 1.198±0.06 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | <64.52mg/ml in DMSO; <64.52mg/ml in ethanol |
| pka | 14.77±0.70(Predicted) |
Safety information for 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
Computed Descriptors for 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
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