4,6-BIS(BENZOYLAMINO)-1,3-BENZENEDICARBOXYLIC ACID
Synonym(s):5-Carboxy-2,4-dibenzamidobenzoic acid
- CAS NO.：70553-45-6
- Empirical Formula: C22H16N2O6
- Molecular Weight: 404.37
- MDL number: MFCD00334657
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is 4,6-BIS(BENZOYLAMINO)-1,3-BENZENEDICARBOXYLIC ACID?
The Uses of 4,6-BIS(BENZOYLAMINO)-1,3-BENZENEDICARBOXYLIC ACID
NS 3763 is a selective non-competitive kainate receptor antagonist.
Biological Activity
Selective non-competitive kainate receptor antagonist; displays selectivity for GLU K5 subunit-containing receptors (IC 50 values are 1.6 and > 30 mM for homomeric GLU K5 and GLU K6 receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC 50 >> 30 mM).
Properties of 4,6-BIS(BENZOYLAMINO)-1,3-BENZENEDICARBOXYLIC ACID
| storage temp. | 2-8°C |
| solubility | DMSO: ~24 mg/mL |
| form | solid |
| color | off-white |
Safety information for 4,6-BIS(BENZOYLAMINO)-1,3-BENZENEDICARBOXYLIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..… |
Computed Descriptors for 4,6-BIS(BENZOYLAMINO)-1,3-BENZENEDICARBOXYLIC ACID
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