4,4'-propylenebis(piperazine-2,6-dione)
- CAS NO.：21416-67-1
- Empirical Formula: C11H16N4O4
- Molecular Weight: 268.27
- MDL number: MFCD00430424
- EINECS: 244-379-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:12
What is 4,4'-propylenebis(piperazine-2,6-dione) ?
The Uses of 4,4'-propylenebis(piperazine-2,6-dione)
Razoxane is an inhibitor of Topo II.
What are the applications of Application
Razoxane is an inhibitor of Topo II
Definition
ChEBI: Razoxane is a N-alkylpiperazine.
Safety Profile
Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Properties of 4,4'-propylenebis(piperazine-2,6-dione)
| Melting point: | 237-239° |
| Boiling point: | 411.43°C (rough estimate) |
| Density | 1.2576 (rough estimate) |
| refractive index | 1.6081 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO: soluble40mg/mL |
| pka | 11.00±0.20(Predicted) |
| form | solid |
| color | White to off-white |
| Water Solubility | 3g/L(25 ºC) |
Safety information for 4,4'-propylenebis(piperazine-2,6-dione)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4,4'-propylenebis(piperazine-2,6-dione)
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium 3-Bromopyrazole (3aR,4R,5R,6aS)-hexahydro-5-Triethyl silyloxy-4-((E)-3-oxo-5-phenylpent-1- enyl)cyclopenta[b]furan-2-one. 1-Chlorocarbonyl-4-piperidinopiperidine 1-Bromo-4-phenyl-2-Butanone 4-Amino-2-fluoro-N-methylbenzamide 1,1'-Carbonyldiimidazole SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTIONRelated products of tetrahydrofuran
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