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HomeProduct name list4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

Synonym(s):Fluolead

4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride Structural

What is 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride?

Chemical properties

White powder

The Uses of 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride is a deoxofluorination reagent used in an improved method of synthesis of arylsulfur trifluorides.

The Uses of 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

Air and thermally stable alternative to DAST. Efficient deoxofluorinating agent for a wide variety of substrates.

The Uses of 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

Features:

  • Tolerance of many functional groups
  • Highly selective functionalization
  • Highly efficient and broad reaction scope
  • Mild reaction conditions

Generally superior reactivity and selectivity to SF4 and easier and safer to handle.

Shown to promote nucleophilic deoxofluorination reactions and exhibits excellent thermal stability, up to 150 °C, therefore rendering it safely applicable in a variety of processes, including industrial scale production.


Novel fluorinating reagent applicable to a variety of chemical processes (Scheme 1).

Refer to the Datasheet for more information on Fluolead?: A Novel New Versatile Fluorinating Agent

General Description

4-tert-Butyl-2,6-dimethylphenylsulfur trifluoride is a thermally stable, easy-to-handle, versatile deoxofluorinating agent that also shows high stability on contact with water. It is a superior alternative to diethylaminosulfur trifluoride (DAST).

Properties of 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

Melting point: 62-68 °C
Boiling point: 92-93℃ (0.5 Torr)
Density  1.07±0.1 g/cm3(Predicted)
storage temp.  0-10°C
form  crystal
color  white to off-white

Safety information for 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H290:Corrosive to Metals
H301:Acute toxicity,oral
H314:Skin corrosion/irritation
Precautionary Statement Codes P234:Keep only in original container.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P310:Immediately call a POISON CENTER or doctor/physician.
P390:Absorb spillage to prevent material damage.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.
P406:Store in corrosive resistant/… container with a resistant inner liner.
P501:Dispose of contents/container to..…

Computed Descriptors for 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride

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