4-PHENYL-1,2,3-THIADIAZOLE
- CAS NO.：25445-77-6
- Empirical Formula: C8H6N2S
- Molecular Weight: 162.21
- MDL number: MFCD00087232
- EINECS: 636-735-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-21 10:59:17
What is 4-PHENYL-1,2,3-THIADIAZOLE?
Description
Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolizes substituted amines, CYP2E1 metabolizes various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-
Chemical properties
Off-white to light brown solid
Synthesis Reference(s)
Journal of Medicinal Chemistry, 28, p. 442, 1985 DOI: 10.1021/jm00382a009
Properties of 4-PHENYL-1,2,3-THIADIAZOLE
| Melting point: | 78°C |
| Boiling point: | 100°C 1,5mm |
| Density | 1.241±0.06 g/cm3(Predicted) |
| Flash point: | 100°C/1.5mm |
| storage temp. | Store at -20°C |
| solubility | DMF: 3 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml |
| form | A crystalline solid |
| pka | -4.23±0.22(Predicted) |
| BRN | 119480 |
Safety information for 4-PHENYL-1,2,3-THIADIAZOLE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-PHENYL-1,2,3-THIADIAZOLE
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 Tubulysin B Tubulysin I Tubulysin G 3-Methyl pyridine-4-carboxylicacid 2,6-dichloro-3-nitropyridin-4-amine 2-cyano-6-chloro-3-nitropyridine 3-bromo-6-chloro-2-methyl-5-nitropyridine methyl 1-amino-7-(benzyloxy)thieno[3,2-f]quinoline-2-carboxylate 5-Methoxy pyridine-2-methanol 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell Imeglimin Hydrochloride IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-Chloro-3-(chloromethyl)pyridine 4-Bromo-N,N-bis(4-iodophenyl)aniline Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester Methyl 4-amino-3-(pyrrolidin-1-yl)benzoateRelated products of tetrahydrofuran
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