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HomeProduct name list4-O-(Carboxymethyl)rifamycin

4-O-(Carboxymethyl)rifamycin

4-O-(Carboxymethyl)rifamycin Structural

What is 4-O-(Carboxymethyl)rifamycin?

The Uses of 4-O-(Carboxymethyl)rifamycin

A Rifamycin (R508200) derivative as antibacterial agent.

The Uses of 4-O-(Carboxymethyl)rifamycin

Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin (R508200) derivative as antibacterial agent.

What are the applications of Application

Rifamycin B is Rifamycin B is a Rifamycin derivative used as antibacterial agent

Definition

ChEBI: Rifamycin B is a carboxylic acid, an acetate ester, an organic heterotetracyclic compound and a member of rifamycins. It is a conjugate acid of a rifamycin B(2-).

Purification Methods

Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.]

Properties of 4-O-(Carboxymethyl)rifamycin

Melting point: 300° (dec 160-164°)
Boiling point: 730.16°C (rough estimate)
alpha  D20 -11° (methanol)
Density  1.2421 (rough estimate)
refractive index  1.5350 (estimate)
solubility  DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
form  neat
pka 2.69±0.10(Predicted)
BRN  604953
Stability: Unstable in solution

Safety information for 4-O-(Carboxymethyl)rifamycin

Computed Descriptors for 4-O-(Carboxymethyl)rifamycin

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