4-HYDROXYPHENOXYACETIC ACID
- CAS NO.：1878-84-8
- Empirical Formula: C8H8O4
- Molecular Weight: 168.15
- MDL number: MFCD00014362
- EINECS: 217-525-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-14 17:42:33
What is 4-HYDROXYPHENOXYACETIC ACID?
Chemical properties
off-white to beige fine crystalline powder
The Uses of 4-HYDROXYPHENOXYACETIC ACID
2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.
Definition
ChEBI: 4-Hydroxypheoxyacetate is a monocarboxylic acid.
General Description
(4-Hydroxyphenoxy)acetic acid along with formaldehyde ammonium salt forms a polyaromatic anionic compound RG-13577. RG-13577 mimics the synthetic heparin and specifically binds to the vascular smooth muscle cells (SMCs) and inhibits their proliferative growth. In the molecules of (4-hydroxyphenoxy)acetic acid, the carboxyl groups are held together by R22(8) hydrogen bonds.
Properties of 4-HYDROXYPHENOXYACETIC ACID
| Melting point: | 154-157 °C (lit.) |
| Boiling point: | 372.6±17.0 °C(Predicted) |
| Density | 1.367±0.06 g/cm3(Predicted) |
| solubility | soluble in Methanol |
| form | Fine Crystalline Powder |
| pka | 3.27±0.10(Predicted) |
| color | Off-white to beige |
| BRN | 1952779 |
| CAS DataBase Reference | 1878-84-8(CAS DataBase Reference) |
| EPA Substance Registry System | Acetic acid, (4-hydroxyphenoxy)- (1878-84-8) |
Safety information for 4-HYDROXYPHENOXYACETIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-HYDROXYPHENOXYACETIC ACID
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Rimegepant Impurity 3 Ivermectin EP Impurity B Fosfomycin EP impurity D Tubulysin B Tubulysin M Tubulysin E Tubulysin C Tubulysin G Tubulysin A Potassium HMDS (1.0 M in THF) Calcium Sodium Phosphosilicate IH Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(4-Bromopyridin-2-yl)acetonitrile 5-Aminophthalazine 4-(Azidomethyl)-3-chloropyridine 3,6-Bis(4-bromophenyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dioneRelated products of tetrahydrofuran
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