4-METHYLUMBELLIFERYL OLEATE
Synonym(s):Oleic acid 4-methylumbelliferyl ester
- CAS NO.：18323-58-5
- Empirical Formula: C28H40O4
- Molecular Weight: 440.61
- MDL number: MFCD00076095
- EINECS: 242-210-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-06 18:33:45
What is 4-METHYLUMBELLIFERYL OLEATE?
Description
4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.
Chemical properties
Colourless Oil
The Uses of 4-METHYLUMBELLIFERYL OLEATE
4-Methylumbelliferyl oleate can act as Fatty acyl esters for use as fluorogenic substrates to continuously follow the hydrolytic activity of carboxylesterases, such as acid and alkaline lipases.
The Uses of 4-METHYLUMBELLIFERYL OLEATE
Fluorogenic substrate for lipases.
The Uses of 4-METHYLUMBELLIFERYL OLEATE
4-Methylumbelliferyl oleate has been used:
- as a substrate to assay the activity of non-specific esterases
- to determine lipase activity
- as a substrate to evaluate pancreatic lipase inhibitory activity
What are the applications of Application
4-Methylumbelliferyl Oleate is a fluorogenic substrate for lipases
Properties of 4-METHYLUMBELLIFERYL OLEATE
| Melting point: | 37-38 °C (lit.) |
| Boiling point: | 471.81°C (rough estimate) |
| Density | 1.023 |
| refractive index | 1.4840 (estimate) |
| Flash point: | 281.3℃ |
| storage temp. | -20°C |
| solubility | 2-methoxyethanol: soluble |
| form | Solid |
| color | Colorless to Pale Yellow Oil |
| BRN | 4887028 |
| CAS DataBase Reference | 18323-58-5(CAS DataBase Reference) |
Safety information for 4-METHYLUMBELLIFERYL OLEATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-METHYLUMBELLIFERYL OLEATE
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