4-Methylumbelliferyl-beta-D-glucuronide
Synonym(s):4-Methylumbelliferyl-β-D-glucuronide - CAS 6160-80-1 - Calbiochem;MUG
- CAS NO.:6160-80-1
- Empirical Formula: C16H16O9
- Molecular Weight: 352.3
- MDL number: MFCD00036772
- EINECS: 228-186-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-13 17:19:14
What is 4-Methylumbelliferyl-beta-D-glucuronide?
Description
4-Methylumbelliferyl-beta-D-glucuronide is a fluorescent substrate of β-glucuronidase. Once cleaved, 4-Methylumbelliferyl-beta-D-glucuronide yields blue fluorescence seen under UV light which is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively. It is ideal for working with Escherichia coli and plant molecular studies.
Chemical properties
Crystalline
The Uses of 4-Methylumbelliferyl-beta-D-glucuronide
4-Methylumbelliferyl-beta-D-glucuronide is a substrate for glucuronidase. Also used as a test for coliform bacteria in water. Fluorescence: max. Abs. 316nm; max. Em. 375nm; e x 10-3: 12
The Uses of 4-Methylumbelliferyl-beta-D-glucuronide
Substrate for ?-D-glucuronidase assay. MUG is widely used as component of selective microbial culture media.
The Uses of 4-Methylumbelliferyl-beta-D-glucuronide
4-Methylumbelliferyl β-D-glucuronide dihydrate is a useful building block and a fluorophore.
What are the applications of Application
4-Methylumbelliferyl β-D-glucuronide is a useful substrate of beta-glucuronidase
What are the applications of Application
4-Methylumbelliferyl β-D-glucuronide dihydrate is a fluorogenic substrate for glucuronidase
Definition
ChEBI: A beta-D-glucosiduronic acid having a 4-methylumbelliferyl substituent at the anomeric position.
Properties of 4-Methylumbelliferyl-beta-D-glucuronide
Melting point: | 102 °C |
Boiling point: | 683.1±55.0 °C(Predicted) |
alpha | -105 º (c=0.25, water 30 ºC) |
Density | 1.632±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | Methanol (Slightly), Water (Slightly) |
form | White crystalline solid |
pka | 2.76±0.70(Predicted) |
color | White |
Water Solubility | slightly soluble |
Sensitive | Moisture Sensitive |
CAS DataBase Reference | 6160-80-1(CAS DataBase Reference) |
EPA Substance Registry System | .beta.-D-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl (6160-80-1) |
Safety information for 4-Methylumbelliferyl-beta-D-glucuronide
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Methylumbelliferyl-beta-D-glucuronide
InChIKey | ARQXEQLMMNGFDU-YXNYVWNSSA-N |
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CNS Labs Private Limited
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