4-Methylumbelliferyl-beta-D-glucuronide

Synonym(s):4-Methylumbelliferyl-β-D-glucuronide - CAS 6160-80-1 - Calbiochem;MUG

CAS NO.：6160-80-1
Empirical Formula: C16H16O9
Molecular Weight: 352.3
MDL number: MFCD00036772
EINECS: 228-186-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:08:52

4-Methylumbelliferyl-beta-D-glucuronide Structural

What is 4-Methylumbelliferyl-beta-D-glucuronide?

Description

4-Methylumbelliferyl-beta-D-glucuronide is a fluorescent substrate of β-glucuronidase. Once cleaved, 4-Methylumbelliferyl-beta-D-glucuronide yields blue fluorescence seen under UV light which is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively. It is ideal for working with Escherichia coli and plant molecular studies.

Chemical properties

Crystalline

The Uses of 4-Methylumbelliferyl-beta-D-glucuronide

Substrate for ?-D-glucuronidase assay. MUG is widely used as component of selective microbial culture media.

The Uses of 4-Methylumbelliferyl-beta-D-glucuronide

4-Methylumbelliferyl-beta-D-glucuronide is a substrate for glucuronidase. Also used as a test for coliform bacteria in water. Fluorescence: max. Abs. 316nm; max. Em. 375nm; e x 10-3: 12

The Uses of 4-Methylumbelliferyl-beta-D-glucuronide

4-Methylumbelliferyl β-D-glucuronide dihydrate is a useful building block and a fluorophore.

Definition

ChEBI: A beta-D-glucosiduronic acid having a 4-methylumbelliferyl substituent at the anomeric position.

What are the applications of Application

4-Methylumbelliferyl β-D-glucuronide is a useful substrate of beta-glucuronidase

What are the applications of Application

4-Methylumbelliferyl β-D-glucuronide dihydrate is a fluorogenic substrate for glucuronidase

Properties of 4-Methylumbelliferyl-beta-D-glucuronide

Melting point:	102 °C
Boiling point:	683.1±55.0 °C(Predicted)
alpha	-105 º (c=0.25, water 30 ºC)
Density	1.632±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	Methanol (Slightly), Water (Slightly)
form	White crystalline solid
pka	2.76±0.70(Predicted)
color	White
Water Solubility	slightly soluble
Sensitive	Moisture Sensitive
CAS DataBase Reference	6160-80-1(CAS DataBase Reference)
EPA Substance Registry System	.beta.-D-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl (6160-80-1)

Safety information for 4-Methylumbelliferyl-beta-D-glucuronide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.