4-Methoxyphenylboronic acid

Synonym(s):4-Methoxybenzeneboronic acid;p-Anisylboronic acid;p-Methoxybenzeneboronic acid;4-Anisylboronic acid;(p-Methoxyphenyl)boronic acid

CAS NO.：5720-07-0
Empirical Formula: C7H9BO3
Molecular Weight: 151.96
MDL number: MFCD00039139
EINECS: 611-482-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-10-11 09:51:14

What is 4-Methoxyphenylboronic acid?

Chemical properties

white to light beige crystalline powder

The Uses of 4-Methoxyphenylboronic acid

4-Methoxyphenylboronic acid can be used as a common organic reagent in Suzuki coupling reactions to study the N-arylation of imidazoles and amines catalyzed by copper exchange of calcium fluorophosphates.Reagent used in the preparation of various biological inhibitors.

The Uses of 4-Methoxyphenylboronic acid

4-Methoxyphenylboronic acid is a reagent used for
Suzuki-Miyaura cross-coupling reactions
Pd-catalyzed direct arylation
Highly effective synthesis using palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water
Palladium-catalyzed stereoselective Heck-type reaction
Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence
Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides
Ruthenium catalyzed direct arylation
Rh-catalyzed asymmetric conjugate addition

The Uses of 4-Methoxyphenylboronic acid

suzuki reaction

Safety

4-Methoxyphenylboronic acid poses certain safety concerns. It may cause respiratory irritation and serious eye irritation. To ensure safety, it is advised to avoid inhaling the dust, fumes, gases, mists, vapors, or spray of the compound.

Properties of 4-Methoxyphenylboronic acid

Melting point:	204-206 °C(lit.)
Boiling point:	306.8±44.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in dimethyl sulfoxide and methanol.
form	Crystalline Powder
pka	8.96±0.10(Predicted)
color	White to light beige
BRN	2936912
CAS DataBase Reference	5720-07-0(CAS DataBase Reference)

Safety information for 4-Methoxyphenylboronic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.