4-METHOXYPHENYL ISOTHIOCYANATE

CAS NO.：2284-20-0
Empirical Formula: C8H7NOS
Molecular Weight: 165.21
MDL number: MFCD00011676
EINECS: 218-921-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-25 18:01:03

What is 4-METHOXYPHENYL ISOTHIOCYANATE?

Chemical properties

clear yellow liquid after melting

The Uses of 4-METHOXYPHENYL ISOTHIOCYANATE

4-Methoxyphenyl isothiocyanate has been used in the synthesis of 3-benzyl-2-(4-methoxyphenyl)-3H-[1,2,4]triazolo-[5,1-b]quinazolin-9-one and 2-{[4-amino-3-(4-methylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetyl}-N-arylhydrazinecarbothioamides.

What are the applications of Application

4-Methoxyphenyl isothiocyanate is a synthesis reagent

Synthesis Reference(s)

Tetrahedron Letters, 38, p. 1597, 1997 DOI: 10.1016/S0040-4039(97)00121-4

Properties of 4-METHOXYPHENYL ISOTHIOCYANATE

Melting point:	18 °C(lit.)
Boiling point:	280-281 °C(lit.)
Density	1.196 g/mL at 25 °C(lit.)
refractive index	n20/D 1.653(lit.)
Flash point:	>230 °F
storage temp.	Store below +30°C.
form	powder to lump to clear liquid
Specific Gravity	1.196
color	White or Colorless to Yellow
Water Solubility	It hydrolyzes in water.
Sensitive	Moisture Sensitive
BRN	606967
CAS DataBase Reference	2284-20-0(CAS DataBase Reference)

Safety information for 4-METHOXYPHENYL ISOTHIOCYANATE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Health Hazard GHS08
GHS Hazard Statements	H314:Skin corrosion/irritation H317:Sensitisation, Skin H334:Sensitisation, respiratory
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.