4-MERCAPTOPHENYLACETIC ACID
- CAS NO.:39161-84-7
- Empirical Formula: C8H8O2S
- Molecular Weight: 168.21
- MDL number: MFCD00797617
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:40
What is 4-MERCAPTOPHENYLACETIC ACID?
Chemical properties
4-MERCAPTOPHENYLACETIC ACID is White Powder
The Uses of 4-MERCAPTOPHENYLACETIC ACID
4-Mercaptophenylacetic acid has been used in the preparation of small ubiquitin-like modifier peptides from bis(2-sulfanylethyl)amido peptide via sequential native chemical ligation.
It can be used:
- On-resin preparation of peptide-α thiophenylesters which are used in a chemical ligation process for the chemical synthesis of peptides.
- In one pot deprotection of (acetamido-methyl)cysteine following native chemical ligation and/or desulfurization method for the preparation of peptides.
- Palladium facilitated deprotection of N-terminal cysteine through native chemical ligation method for the preparation of synthetically challenging proteins.
The Uses of 4-MERCAPTOPHENYLACETIC ACID
4-MERCAPTOPHENYLACETIC ACID is a redox buffer that increases the folding rate of disulfide-containing proteins realative to traditional buffers such as glutathione and glutathione-disulfide. A useful synthetic intermediate for the preparation of novel antiinflammatory agents.
What are the applications of Application
4-Mercaptophenylacetic Acid is a redox buffer that increases the folding rate of disulfide-containing proteins
Properties of 4-MERCAPTOPHENYLACETIC ACID
Melting point: | 105-109 °C (lit.) |
Boiling point: | 336.0±17.0 °C(Predicted) |
Density | 1.299±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Acetonitrile (Slightly), DMSO (Slightly) |
pka | 4.21±0.10(Predicted) |
form | Solid |
color | Off-White |
Water Solubility | Slightly soluble in water. Soluble in Dichloromethane, Ethanol and Methanol |
Sensitive | Air Sensitive |
Safety information for 4-MERCAPTOPHENYLACETIC ACID
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for 4-MERCAPTOPHENYLACETIC ACID
4-MERCAPTOPHENYLACETIC ACID manufacturer
Sintilla Medcoms Pvt Ltd
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Aventus Labs
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Phone:+919324342304
Whatsapp: +91-9324342304
product: 4-Mercaptophenylacetic acid 98%
Syn Finechem Laboratories Pvt Ltd.
1Y
Phone:+91-9848230784
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product: 4-Mercaptophenylacetic acid 39161-84-7 98%
BASR Fine Chemicals Pvt. Ltd.
1Y
Phone:+91-9848230391
Whatsapp: +91-9848230391
product: 39161-84-7 98%
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alpha-Methyl-4-((1-methylethyl)thio)benzeneacetic acid
[4-(ETHYLSULFONYL)PHENYL]ACETIC ACID
4-(TRIFLUOROMETHYLTHIO)PHENYLACETIC ACID
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4-Methylsulphonylphenylacetic acid
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