4-Mercaptophenol

Synonym(s):4-Hydroxythiophenol

CAS NO.：637-89-8
Empirical Formula: C6H6OS
Molecular Weight: 126.18
MDL number: MFCD00004850
EINECS: 211-307-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 13:37:16

What is 4-Mercaptophenol?

Chemical properties

Clear colorless to light yellow solid or liquid

The Uses of 4-Mercaptophenol

4-Mercaptophenol was used as a resin monomer in the study of the different gold nanocrystal core-resin shell structures.

The Uses of 4-Mercaptophenol

4-Mercaptophenol (MPH) has been used to study the adsorption of MPH on silver coated polystyrene nanospheres by time-dependent surface-enhanced Raman scattering (SERS) spectroscopy.
4-Mercaptophenol may be used in the preparation of silylated monomer, which was employed for the synthesis of hyperbranched poly(ester-imide). 4-Mercaptophenol (H-4MP) reacts with metal tert-butoxides ([M(OBu^t)₄]) to yield the following Group 4 phenoxy-thiols:

[(HOBu^t)(4MP)₃M(μ-4MP)]₂, where M = Ti, Zr, Hf
[(py)₂M(4MP)], where M = Ti, Zr; py = pyridine
[(py)(4MP)₃Hf(μ-4MP)]₂

4-Mercaptophenol may be used in the synthesis of the following:

poly(ethersulfide)s via silylation followed by polycondensation with 2,6-dichloropyridine or 3,6-dichloropyridazine
2,6-di-tertiarybutyl-4-mercaptophenol via Friedel-Craft′s alkylation with tert-butyl chloride in presence of a lewis acid

What are the applications of Application

4-Mercaptophenol is used to improve charge separation in PbSe quantum dots (QDs) as sensitizers for TiO2.

General Description

The density function theory calculations were performed to infer the IR and Raman spectra for 4-mercaptophenol molecule.

Properties of 4-Mercaptophenol

Melting point:	33-35 °C(lit.)
Boiling point:	149-150 °C25 mm Hg(lit.)
Density	1.255
refractive index	1.5101 (estimate)
Flash point:	>230 °F
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	6.82±0.10(Predicted)
form	Liquid or Low Melting Solid
color	Clear colorless to light yellow
Water Solubility	soluble
Sensitive	Air Sensitive
BRN	2039306
Stability:	Stability Air sensitive. Incompatible with oxidizing agents.
CAS DataBase Reference	637-89-8(CAS DataBase Reference)
NIST Chemistry Reference	4-Mercaptophenol(637-89-8)
EPA Substance Registry System	Phenol, 4-mercapto- (637-89-8)

Safety information for 4-Mercaptophenol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.