4'-Iodoacetophenone

CAS NO.：13329-40-3
Empirical Formula: C8H7IO
Molecular Weight: 246.05
MDL number: MFCD00045320
EINECS: 236-372-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-28 16:56:32

What is 4'-Iodoacetophenone?

Chemical properties

Pale brown to brown crystalline powder

The Uses of 4'-Iodoacetophenone

Synthesis of quinoline-based potential anticancer agents. Substrate for palladium-catalyzed coupling reactions

Synthesis Reference(s)

Journal of the American Chemical Society, 94, p. 5106, 1972 DOI: 10.1021/ja00769a066
The Journal of Organic Chemistry, 48, p. 4394, 1983 DOI: 10.1021/jo00171a050

General Description

Pd(0)-catalyzed cross coupling reaction of 4′-iodoacetophenone with siloxane has been reported. Heck-Mizoroki reactions of 4′-iodoacetophenone with styrene catalyzed by Pd nanoparticles in the flow reactor has been reported.

Properties of 4'-Iodoacetophenone

Melting point:	82-84 °C(lit.)
Boiling point:	142-144 °C(Press: 12 Torr)
Density	1.7411 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Crystalline Powder
color	Pale brown to brown
Water Solubility	Easily soluble in water.
Sensitive	Light Sensitive
BRN	1857412
CAS DataBase Reference	13329-40-3(CAS DataBase Reference)
NIST Chemistry Reference	4-Iodoacetophenone(13329-40-3)

Safety information for 4'-Iodoacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.