4-IODO-PYRIDIN-3-OL
- CAS NO.：188057-20-7
- Empirical Formula: C5H4INO
- Molecular Weight: 221
- MDL number: MFCD09030242
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-03-13 11:54:02
What is 4-IODO-PYRIDIN-3-OL?
Description
4-Iodo-3-hydroxypyridine is an organic intermediate, commonly used in the synthesis of various pharmaceutical and chemical products. It is reported in the literature that 4-iodo-3-hydroxypyridine can be prepared from 2-chloro-4-iodopyridine in one step or from 3-hydroxypyridine in three steps.
What are the applications of Application
4-Iodo-3-hydroxypyridine is an organic intermediate and pharmaceutical intermediate, which is commonly used in the synthesis of various pharmaceutical and chemical products and in laboratory research and development processes.
Synthesis
4-Iodo-3-hydroxypyridine can be prepared by reacting 3-hydroxypyridine, potassium tert-butoxide, and methoxymethyl chloride in a nitrogen atmosphere.
Properties of 4-IODO-PYRIDIN-3-OL
| Melting point: | 196-200℃ |
| Boiling point: | 296.6±20.0 °C(Predicted) |
| Density | 2.142±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 6.87±0.10(Predicted) |
Safety information for 4-IODO-PYRIDIN-3-OL
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P233:Keep container tightly closed. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304:IF INHALED: P312:Call a POISON CENTER or doctor/physician if you feel unwell. P321:Specific treatment (see … on this label). P340:Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P403:Store in a well-ventilated place. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-IODO-PYRIDIN-3-OL
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