4-Hydroxypyrimidine

Synonym(s):4(3H)-Pyrimidone;4-Hydroxypyrimidine;4-Pyrimidinol

CAS NO.：51953-17-4
Empirical Formula: C4H4N2O
Molecular Weight: 96.09
MDL number: MFCD00167178
EINECS: 257-545-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 4-Hydroxypyrimidine?

Chemical properties

white to slightly yellow powder

Hazard

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Enzyme inhibitor

This hygroscopic pyrimidine, also known as 4-hydroxypyrimidine and 4- pyrimidinol (FW = 96.09 g/mol), inhibits both hypoxanthine(guanine) and xanthine phosphoribosyltransferases.

Properties of 4-Hydroxypyrimidine

Melting point:	166-169 °C(lit.)
Boiling point:	179.58°C (rough estimate)
Density	1.2604 (rough estimate)
refractive index	1.4610 (estimate)
storage temp.	0-6°C
form	Powder
pka	pK1:1.85(＋1);pK2:8.59(0) (25°C)
color	White to slightly yellow
Water Solubility	270.3g/L(20 ºC)
BRN	106975
CAS DataBase Reference	51953-17-4(CAS DataBase Reference)

Safety information for 4-Hydroxypyrimidine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed.