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HomeProduct name list4-Hydroxyphenylglycolic acid

4-Hydroxyphenylglycolic acid

  • CAS NO.:1198-84-1
  • Empirical Formula: C8H8O4
  • Molecular Weight: 168.15
  • MDL number: MFCD00004234
  • EINECS: 214-839-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:30
4-Hydroxyphenylglycolic acid Structural

What is 4-Hydroxyphenylglycolic acid?

Chemical properties

off-white crystalline powder

The Uses of 4-Hydroxyphenylglycolic acid

4-Hydroxymandelic Acid is a useful synthetic intermediate in the synthesis of Hydroxyatenolol (H802480); a metabolite of Atenolol (A790075) which is a cardioselective β-adrenergic blocker, antihypertensive, antianginal, and antiarrhythmic (class II).

Definition

ChEBI: A 2-hydroxy carboxylic acid that is mandelic acid bearing a phenolic hydroxy substituent at position 4.

Properties of 4-Hydroxyphenylglycolic acid

Melting point: 82-85 °C(lit.)
Boiling point: 405.4±30.0 °C(Predicted)
Density  1.480±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Soluble in DMSO
form  Solid
pka 3.51±0.10(Predicted)
color  White to pink
CAS DataBase Reference 1198-84-1(CAS DataBase Reference)
EPA Substance Registry System Benzeneacetic acid, ?,4-dihydroxy- (1198-84-1)

Safety information for 4-Hydroxyphenylglycolic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-Hydroxyphenylglycolic acid

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