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HomeProduct name list4-HYDROXY-4-PHENYLPIPERIDINE

4-HYDROXY-4-PHENYLPIPERIDINE

Synonym(s):4-Phenyl-4-piperidinol

  • CAS NO.:40807-61-2
  • Empirical Formula: C11H15NO
  • Molecular Weight: 177.24
  • MDL number: MFCD00006000
  • EINECS: 255-089-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:28
4-HYDROXY-4-PHENYLPIPERIDINE Structural

What is 4-HYDROXY-4-PHENYLPIPERIDINE?

The Uses of 4-HYDROXY-4-PHENYLPIPERIDINE

Reactant for synthesis of:

  • Diaminotriazine hNav1.7 inhibitors
  • Selective σ?ligands
  • Glycogen synthase kinase-3β?inhibitors
  • Diphenylbutylpiperidines as cell autophagy inducers
  • Malonyl-coA decarboxylase inhibitors with antiobesity and antidiabetic activities
  • Selective dopamine D2 receptor antagonists

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 1702, 1956 DOI: 10.1021/ja01589a060

Properties of 4-HYDROXY-4-PHENYLPIPERIDINE

Melting point: 157-161 °C(lit.)
Boiling point: 317.9±42.0 °C(Predicted)
Density  1.093
storage temp.  2-8°C(protect from light)
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 14.13±0.20(Predicted)
color  Pale brown
BRN  141577
CAS DataBase Reference 40807-61-2(CAS DataBase Reference)

Safety information for 4-HYDROXY-4-PHENYLPIPERIDINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 4-HYDROXY-4-PHENYLPIPERIDINE

InChIKey KQKFQBTWXOGINC-UHFFFAOYSA-N

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