4-(DIMETHYLAMINO)BENZONITRILE

Synonym(s):4-Cyano-N,N-dimethylaniline;DMABN

CAS NO.：1197-19-9
Empirical Formula: C9H10N2
Molecular Weight: 146.19
MDL number: MFCD00001815
EINECS: 214-819-8
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

4-(DIMETHYLAMINO)BENZONITRILE Structural

What is 4-(DIMETHYLAMINO)BENZONITRILE?

Chemical properties

light brown crystalline powder

The Uses of 4-(DIMETHYLAMINO)BENZONITRILE

4-(Dimethylamino)benzonitrile is used in predicting the carcinogenicity of aromatic amine derivative in UK EMS collaborative study.

The Uses of 4-(DIMETHYLAMINO)BENZONITRILE

4-(Dimethylamino)benzonitrile can be used in the synthesis of 3,6-diphenyl-2,5-dihydro-pyrrolo[3,4-c]pyrrole-1,4-dione derivatives.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 4035, 1995 DOI: 10.1016/0040-4039(95)00710-T

General Description

4-(Dimethylamino)benzonitrile is extensively used in photophysical studies due to its ability to undergo intramolecular charge transfer (ICT) from the dimethylamino moiety to the cyanophenyl moiety on photo-excitation leading to the appearance of dual fluorescence.

Properties of 4-(DIMETHYLAMINO)BENZONITRILE

Melting point:	72-75 °C(lit.)
Boiling point:	318 °C(lit.)
Density	1.3346 (rough estimate)
refractive index	1.5600 (estimate)
Flash point:	317-319°C
solubility	soluble in Methanol
form	Crystalline Powder
pka	1.61±0.12(Predicted)
color	Light brown
BRN	971606
InChI	InChI=1S/C9H10N2/c1-11(2)9-5-3-8(7-10)4-6-9/h3-6H,1-2H3
CAS DataBase Reference	1197-19-9(CAS DataBase Reference)
EPA Substance Registry System	Benzonitrile, 4-(dimethylamino)- (1197-19-9)

Safety information for 4-(DIMETHYLAMINO)BENZONITRILE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.