4-Chlorophenylacetone
- CAS NO.:5586-88-9
- Empirical Formula: C9H9ClO
- Molecular Weight: 168.62
- MDL number: MFCD00045214
- EINECS: 226-986-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-26 14:13:49
What is 4-Chlorophenylacetone?
Chemical properties
clear light yellow liquid
The Uses of 4-Chlorophenylacetone
4-Chlorophenylacetone is a phenylacetone derivative used in the preparation of biologically active compounds such as anorectic agents.
Preparation
At present, there are three main synthetic routes for 4-chlorophenylacetone. The first is to synthesize 4-chlorophenylacetone with sodium p-chlorobenzenesulfonate and acetone as raw materials, with a yield of about 54%. The second synthesis route is to synthesize 4-chlorophenylacetone with p-chlorobenzenesulfonyl chloride and chloroacetone as raw materials. The third synthesis route is to synthesize 4-chlorophenylacetone from chloroacetone.
Synthesis Reference(s)
The Journal of Organic Chemistry, 48, p. 2590, 1983 DOI: 10.1021/jo00163a034
Health Hazard
When it contacts with skin and mucous membrane, 4-chlorophenylacetone will cause inflammation, so pay attention to safety when using 4-chlorophenylacetone. This chemical is harmful to environment. It should be prevented from contacting groundwater, waterways or sewage systems. Without government permission, 4-chlorophenylacetone should not be discharged into the surrounding environment.
Properties of 4-Chlorophenylacetone
Melting point: | 6-8 °C |
Boiling point: | 132 °C |
Density | 1.151 |
refractive index | 1.5325-1.5345 |
Flash point: | >110℃ |
storage temp. | Sealed in dry,Room Temperature |
form | Liquid |
color | Clear light yellow |
CAS DataBase Reference | 5586-88-9(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Propanone,p-chlorophenyl-(5586-88-9) |
Safety information for 4-Chlorophenylacetone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H412:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-Chlorophenylacetone
Abamectin manufacturer
Dr. Jagath Reddy's Heterocyclics
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