4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
- CAS NO.：4362-40-7
- Empirical Formula: C6H11ClO2
- Molecular Weight: 150.6
- MDL number: MFCD00046097
- EINECS: 224-452-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE?
Chemical properties
clear colourless to light yellow liquid
The Uses of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is used in biosynthetic preparations.
The Uses of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane may be used in the preparation of 2,2-dimethyl-4-methylene-1,3-dioxolane via dehydrochlorination.
Synthesis Reference(s)
Canadian Journal of Chemistry, 44, p. 1331, 1966 DOI: 10.1139/v66-199
General Description
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is a ketal that can be synthesized by the reaction of 3-chloro-propane-1,2-diol (3-MCPD) with acetone in the presence of p-toluene sulfonic acid.
Properties of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
| Boiling point: | 156-158 °C(lit.) |
| Density | 1.063 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 128 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Colourless |
| Stability: | Volatile |
| CAS DataBase Reference | 4362-40-7 |
| EPA Substance Registry System | 1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl- (4362-40-7) |
Safety information for 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H226:Flammable liquids H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. |
Computed Descriptors for 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
New Products
1-Amino-1-cyclohexanecarboxylic acid 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 6-Bromo-3-iodo-1-methyl-1H-indazole S-Methylisothiosemicarbazide hydroiodide ELECTROLYTIC IRON POWDER 1-Aminocyclobutanecarboxylic acid 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate Decanonitrile N,N'-diallyl-1,3-diaminopropanedihydrochloride 4-(4-Nitrophenyl)piperidine N-(3-Nitrophenyl)cyclopropanecarboxamide (2-amino-2-phenylethyl)(methyl)amine methyl 6-chloro-2-(chloromethyl)nicotinate 2-methoxy-4-methyl-5-nitro pyridine 2-iodo-5-bromo pyridine 2-amino-4-methyl-5-nitro pyridine 4-cyano benzaldehyde 2-hydroxy-5-bromo pyridine 5-Fluoro-2-Oxindole 3,5-Dichloro-2,6-Dimethyl-1h-Pyridin-4-One (S)-1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid (9H-fluoren-9-yl)methyl carbonochloridate 2-methyl-5-nitroanilineRelated products of tetrahydrofuran
![2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.4]NONANE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB3463541.gif)
![2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.11]HEXADECANE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB0379339.gif)
![4-CHLOROMETHYL-2-ISOBUTYL-2-METHYL-[1,3]DIOXOLANE](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB3218992.gif)
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