4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
- CAS NO.：4362-40-7
- Empirical Formula: C6H11ClO2
- Molecular Weight: 150.6
- MDL number: MFCD00046097
- EINECS: 224-452-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 13:37:16
What is 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE?
Chemical properties
clear colourless to light yellow liquid
The Uses of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is used in biosynthetic preparations.
The Uses of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane may be used in the preparation of 2,2-dimethyl-4-methylene-1,3-dioxolane via dehydrochlorination.
Synthesis Reference(s)
Canadian Journal of Chemistry, 44, p. 1331, 1966 DOI: 10.1139/v66-199
General Description
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is a ketal that can be synthesized by the reaction of 3-chloro-propane-1,2-diol (3-MCPD) with acetone in the presence of p-toluene sulfonic acid.
Properties of 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
| Boiling point: | 156-158 °C(lit.) |
| Density | 1.063 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 128 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Colourless |
| Stability: | Volatile |
| CAS DataBase Reference | 4362-40-7 |
| EPA Substance Registry System | 1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl- (4362-40-7) |
Safety information for 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H226:Flammable liquids H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. |
Computed Descriptors for 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 4-Hydrazinobenzoic acid 3,4-Dibenzyloxybenzaldehyde Electrolytic Iron Powder 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 4-HYDROXY BENZYL ALCOHOL 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) S-2-CHLORO PROPIONIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 6-Bromo-3-iodo-1-methyl-1H-indazole 4-Ethylbenzylamine N-(5-Amino-2-methylphenyl)acetamide 2-(BOC-Amino)4-picoline 1-(4-Methylphenylsulfonyl)-1H-1,2,3-benzotriazoleRelated products of tetrahydrofuran
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