Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list4-CHLOROMERCURIBENZOIC ACID

4-CHLOROMERCURIBENZOIC ACID

Synonym(s):4-(Chloromercurio)benzoic acid;4-(Hydroxymercuri)benzoic acid;Dihydrofolate reductase;DYR;N/A

  • CAS NO.:59-85-8
  • Empirical Formula: C7H5ClHgO2
  • Molecular Weight: 357.16
  • MDL number: MFCD00002526
  • EINECS: 200-442-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:19
4-CHLOROMERCURIBENZOIC ACID Structural

What is 4-CHLOROMERCURIBENZOIC ACID?

Chemical properties

4-CHLOROMERCURIBENZOIC ACID is White Solid

The Uses of 4-CHLOROMERCURIBENZOIC ACID

4-CHLOROMERCURIBENZOIC ACID can be used to inhibit some enzymes that require unmodified cysteine residues (e.g., adenylyl cyclase).

The Uses of 4-CHLOROMERCURIBENZOIC ACID

A useful sulfhydryl reagent that reacts with Histidine 225C, a residue of the NhaA-Na/H Antiporter of Escherichia Coli

Definition

ChEBI: P-chloromercuribenzoic acid is a mercuribenzoic acid and a chlorine molecular entity. It is functionally related to a benzoic acid.

Safety Profile

Poison by intraperitoneal route. See also MERCURY COMPOUNDS. When heated to decomposition it emits very toxic fumes of Cland Hg.

Purification Methods

Its suspension in water is stirred with enough 1M NaOH to dissolve most of it: a small amount of insoluble matter is removed by centrifugation. The chloromercuribenzoic acid is then precipitated by adding 1M HCl and centrifuged off. The precipitation is repeated twice. Finally, the precipitate is washed three times with distilled water (by centrifugation), then dried in a thin layer under vacuum over P2O5 [Boyer J Am Chem Soc 76 4331 1954]. Chloromethylphosphonic acid dichloride [1983 -26 -2] M 167.4, b 50o/0.5mm, 52 -53(59)o/2mm, 63-65o/3mm, 78 -79o/10mm, 87 -88o/15mm, 102-103o/30mm, d 4 1.638, n D 1.4971. It is fractionally distilled using a short Claisen column and redistilled. The aniline salt has m 199-201o. The 3 1P NMR has a single peak at -38±2 ppm from 85% H3PO4. [Kinnear & Perren J Chem Soc 3437 1952, NMR: van Wazer et al. J Am Chem Soc 78 5715 1956, McConnell et al. J Org Chem 22 462 1957, Beilstein 1 III 2593, 1 IV 3068.]

Properties of 4-CHLOROMERCURIBENZOIC ACID

Melting point: 287 °C (dec.)(lit.)
storage temp.  -20°C Freezer
solubility  Aqueous Base (Slightly, Heated),
form  solid
BRN  3662892
CAS DataBase Reference 59-85-8(CAS DataBase Reference)
EPA Substance Registry System Mercurate(1-), (4-carboxylatophenyl)chloro-, hydrogen (59-85-8)

Safety information for 4-CHLOROMERCURIBENZOIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 4-CHLOROMERCURIBENZOIC ACID

Related products of tetrahydrofuran

You may like

  • DHFR from mouse CAS
    DHFR from mouse CAS
    View Details
  • 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    99903-60-3
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.