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HomeProduct name list4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

  • CAS NO.:162012-70-6
  • Empirical Formula: C8H3ClFN3O2
  • Molecular Weight: 227.58
  • MDL number: MFCD08063159
  • EINECS: 000-000-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-06-05 17:10:12
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Structural

What is 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE?

The Uses of 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

4-Chloro-7-fluoro-6-nitroquinazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Properties of 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

Boiling point: 395℃
Density  1.649
Flash point: 193℃
storage temp.  Sealed in dry,Store in freezer, under -20°C
pka 0.53±0.70(Predicted)

Safety information for 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

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