4-Aminophthalhydrazide

Synonym(s):6-Amino-2,3-dihydro-1,4-phthalazinedione;Isoluminol

CAS NO.：3682-14-2
Empirical Formula: C8H7N3O2
Molecular Weight: 177.16
MDL number: MFCD00010560
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-19 18:29:52

What is 4-Aminophthalhydrazide?

Chemical properties

Powder

The Uses of 4-Aminophthalhydrazide

4-Aminophthalhydrazide has been used in:

chemiluminescence-based reactive oxygen species (ROS) assay in bone marrow (BM) neutrophils post-Yersinia pseudotuberculosis infection
neutrophil ROS assays post-K. pneumonia exposure
neutrophil ROS assays in response to formylated-methionine-leucine-proline

What are the applications of Application

4-Aminophthalhydrazide is a chemiluminescent molecule

Biochem/physiol Actions

4-Aminophthalhydrazide or isoluminol is a chemiluminescent compound that comprises a phthalazine ring. It is more hydrophilic than luminol. Isoluminol is commercially used in a wide variety of in vitro immunoassays and is a chemiluminescence amplifier for studying reactive oxygen species. It is also useful as an electroluminescence (ECL) biosensor and as a probe for rapid microbial detection.

Properties of 4-Aminophthalhydrazide

Melting point:	300 °C (lit.)
Density	1.433±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Soluble in ammonium hydroxide, sodium carbonate or other base.
form	Solid
pka	10.78±0.20(Predicted)
color	White to Off-White
Sensitive	Air Sensitive
BRN	164804
CAS DataBase Reference	3682-14-2(CAS DataBase Reference)

Safety information for 4-Aminophthalhydrazide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.