4-Amino-6-methoxypyrimidine

CAS NO.：696-45-7
Empirical Formula: C5H7N3O
Molecular Weight: 125.13
MDL number: MFCD00129983
EINECS: 626-150-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 4-Amino-6-methoxypyrimidine?

Chemical properties

White to yellow powder.

The Uses of 4-Amino-6-methoxypyrimidine

6-Methoxy-4-pyrimidinamine is used in the synthesis of carbamothiolacrylamides as selective EP2 antagonists in the treatment of neurodegenerative peripheral diseases. Also used in the preparation of PARP-1 inhibitors.

What are the applications of Application

4-Amino-6-methoxypyrimidine is a chemical used in the synthesis of carbamothiolacrylamides as selective EP2 antagonists

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 15, p. 1121, 1978 DOI: 10.1002/jhet.5570150710

Properties of 4-Amino-6-methoxypyrimidine

Melting point:	157-160 °C (lit.)
Boiling point:	232.57°C (rough estimate)
Density	1.2602 (rough estimate)
refractive index	1.6190 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO, Methanol
pka	4.11±0.10(Predicted)
form	Crystalline Powder
color	White to yellow
CAS DataBase Reference	696-45-7(CAS DataBase Reference)

Safety information for 4-Amino-6-methoxypyrimidine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.