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HomeProduct name list4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

  • CAS NO.:757251-39-1
  • Empirical Formula: C13H12FN3O2
  • Molecular Weight: 261.25
  • MDL number: MFCD09033852
  • EINECS: 692-721-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Structural

What is 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE?

Chemical properties

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide has the appearance of a white to yellow powder or crystals, which is stable and non-reactive under normal conditions of use, storage and transport.

The Uses of 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.

Definition

ChEBI: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide is an aromatic ether.

Properties of 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

Melting point: 143 °C
Boiling point: 459.8±45.0 °C(Predicted)
Density  1.305
vapor pressure  0Pa at 20℃
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
form  Solid
pka 13.92±0.46(Predicted)
color  Orange to Dark Red to Brown
Water Solubility  190mg/L at 20℃

Safety information for 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

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