4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
- CAS NO.：915087-16-0
- Empirical Formula: C21H17F3N4O2S
- Molecular Weight: 446.45
- MDL number: MFCD34471734
- Update Date: 2023-05-15 10:44:02
![4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Structural](https://img.chemicalbook.in/CAS/20180703/GIF/915087-16-0.gif)
What is 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide?
The Uses of 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
Defluoro-MDV 3100 (Defluoro-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.
Properties of 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
| Density | 1.46±0.1 g/cm3(Predicted) |
| solubility | Acetone (Slightly), Chloroform (Slightly) |
| pka | 14.46±0.46(Predicted) |
| form | Solid |
| color | Pale Yellow to Light Yellow |
Safety information for 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
Computed Descriptors for 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
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![4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-](https://img.chemicalbook.in/CAS/20210111/GIF/1289942-55-7.gif)
![[2H6]-Enzalutamide](https://img.chemicalbook.in/CAS/20211123/GIF/1443331-94-9.gif)
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