4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
- CAS NO.:39731-05-0
- Empirical Formula: C19H28N2O4
- Molecular Weight: 348.44
- MDL number: MFCD00869100
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 16:42:15
What is 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER?
The Uses of 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
SDZ 21009 is a 5-HT1A/1B antagonist.
What are the applications of Application
SDZ 21009 is a β-AR, SR-1A, and SR-1B antagonist
Definition
ChEBI: 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid propan-2-yl ester is an isopropyl ester and an indolyl carboxylate ester.
Biological Activity
β -adrenoceptor and 5-HT 1A/1B receptor antagonist. pK B /pA 2 values are 8.3 and 8.0 for 5-HT 1A and 5-HT 1B receptors respectively. Centrally active following systemic administration in vivo .
Properties of 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
Boiling point: | 529.8±50.0 °C(Predicted) |
Density | 1.150±0.06 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
form | Powder |
pka | pKa 8.75 (Uncertain) |
Safety information for 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
Computed Descriptors for 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
New Products
Tubulysin I Tubulysin A (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate 4,4-DIFLUOROPIPERIDINE tetrahydro-4-methyl-2H-pyran 3-Aminocyclobutanone hydrochloride 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 3-FLUOROPYRROLIDINE HYDROCHLORIDE 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Fuel shell (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (2,3-Dihydro- benzofuran-5-yl)- ethanol (S)-3-(3-fluoro- 4-thiomorpholinophenyl) -4-(hydroxymethyl) oxazolidin-2-one Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
Pindolol
4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
4-methoxy-2-methyl-1H-indole
METHYL 4-METHOXY-2-INDOLECARBOXYLATE
4-Hydroxy-2-methylindole
rac Mepindolol-d7
4-Methoxy-1H-indole-2-carboxylic acid
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