4-(2-Aminoethyl)morpholine
Synonym(s):2-Morpholinoethylamine
- CAS NO.：2038-03-1
- Empirical Formula: C6H14N2O
- Molecular Weight: 130.19
- MDL number: MFCD00006182
- EINECS: 218-011-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-25 10:25:48
What is 4-(2-Aminoethyl)morpholine?
Chemical properties
clear colorless to pale yellow liq. after melting
The Uses of 4-(2-Aminoethyl)morpholine
4-(2-Aminoethyl)morpholine is used as a ligand and reacts with nickel(II) nitrite to form trans-bis[4-(2-aminoethyl)morpholine]dinitronickel(II).
The Uses of 4-(2-Aminoethyl)morpholine
4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:
- Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
- Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
- Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
- It is also used as a precursor to synthesize a variety of antimicrobial agents.
Definition
ChEBI: 4-2-Aminoethyl-morpholine is a member of morpholines.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 34, p. 1805, 1991 DOI: 10.1021/jm00110a008
Properties of 4-(2-Aminoethyl)morpholine
| Melting point: | 24 °C |
| Boiling point: | 205 °C(lit.) |
| Density | 0.992 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 347 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Chloroform, Methanol |
| pka | pK1: 4.06(+2);pK2: 9.15(+1) (25°C) |
| form | Liquid After Melting |
| color | Clear colorless to pale yellow |
| Water Solubility | soluble |
| Sensitive | Air Sensitive |
| BRN | 104378 |
| Stability: | Air Sensitive |
| CAS DataBase Reference | 2038-03-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Morpholineethanamine(2038-03-1) |
| EPA Substance Registry System | 4-Morpholineethanamine (2038-03-1) |
Safety information for 4-(2-Aminoethyl)morpholine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-(2-Aminoethyl)morpholine
| InChIKey | RWIVICVCHVMHMU-UHFFFAOYSA-N |
Abamectin manufacturer
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product: 4-Morpholine Ethanamine
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