(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

CAS NO.：291775-59-2
Empirical Formula: C12H19NO4
Molecular Weight: 241.28
MDL number: MFCD11099876
EINECS: 808-164-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-24 19:16:04

What is (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid?

The Uses of (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants.

What are the applications of Application

(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid is a bicyclic structure

Properties of (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

Melting point:	147-152 °C
Boiling point:	371.0±25.0 °C(Predicted)
Density	1.232±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	4.05±0.20(Predicted)
optical activity	[α]22/D -170±10°, c = 1 in chloroform

Safety information for (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H360:Reproductive toxicity H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention.