(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

CAS NO.：149249-91-2
Empirical Formula: C22H27NO3Si
Molecular Weight: 381.54
MDL number: MFCD08273950
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-29 11:48:30

What is (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone?

The Uses of (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone is an intermedaite of 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel (B207800), which is an impurity in the synthesis of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi''s sarcoma.

Properties of (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

Boiling point:	467.2±55.0 °C(Predicted)
Density	1.12
storage temp.	2-8°C
solubility	Dichloromethane, Ether, Ethyl Acetate, Methanol
pka	-4.66±0.60(Predicted)
form	Oil
color	Transparent
CAS DataBase Reference	149249-91-2(CAS DataBase Reference)

Safety information for (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

Computed Descriptors for (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

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