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HomeProduct name list3BETA-HYDROXY-DELTA5-CHOLENIC ACID

3BETA-HYDROXY-DELTA5-CHOLENIC ACID

Synonym(s):3β-Hydroxy-5-cholen-24-oic acid

3BETA-HYDROXY-DELTA5-CHOLENIC ACID Structural

What is 3BETA-HYDROXY-DELTA5-CHOLENIC ACID?

Description

Cholenic acid is a monohydroxy bile acid. It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid . Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis.

The Uses of 3BETA-HYDROXY-DELTA5-CHOLENIC ACID

5-Cholenic Acid-3β-ol is a bile acid of which the metabolism in humans results in the primary bile acids lithocholic acid and chenodeoxycholic. It is found in hgher concentrations in meconium of premature human babies when compared to full term babies.

Definition

ChEBI: 3b-Hydroxy-5-cholenoic acid is a steroid.

Properties of 3BETA-HYDROXY-DELTA5-CHOLENIC ACID

Melting point: 232°C
Boiling point: 522.8±23.0 °C(Predicted)
Density  1.11±0.1 g/cm3(Predicted)
refractive index  -39.5 ° (C=1, Dioxane)
storage temp.  Refrigerator
solubility  Dioxane (Slightly, Sonicated), DMF (Slightly), DMSO (Slightly, Heated,. Sonicate
form  Solid
pka 4.76±0.10(Predicted)
color  White to Pale Yellow
CAS DataBase Reference 5255-17-4

Safety information for 3BETA-HYDROXY-DELTA5-CHOLENIC ACID

Computed Descriptors for 3BETA-HYDROXY-DELTA5-CHOLENIC ACID

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