3BETA-HYDROXY-DELTA5-CHOLENIC ACID
Synonym(s):3β-Hydroxy-5-cholen-24-oic acid
- CAS NO.：5255-17-4
- Empirical Formula: C24H38O3
- Molecular Weight: 374.57
- MDL number: MFCD00069468
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is 3BETA-HYDROXY-DELTA5-CHOLENIC ACID?
Description
Cholenic acid is a monohydroxy bile acid. It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid . Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis.
The Uses of 3BETA-HYDROXY-DELTA5-CHOLENIC ACID
5-Cholenic Acid-3β-ol is a bile acid of which the metabolism in humans results in the primary bile acids lithocholic acid and chenodeoxycholic. It is found in hgher concentrations in meconium of premature human babies when compared to full term babies.
Definition
ChEBI: 3b-Hydroxy-5-cholenoic acid is a steroid.
Properties of 3BETA-HYDROXY-DELTA5-CHOLENIC ACID
| Melting point: | 232°C |
| Boiling point: | 522.8±23.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| refractive index | -39.5 ° (C=1, Dioxane) |
| storage temp. | Refrigerator |
| solubility | Dioxane (Slightly, Sonicated), DMF (Slightly), DMSO (Slightly, Heated,. Sonicate |
| form | Solid |
| pka | 4.76±0.10(Predicted) |
| color | White to Pale Yellow |
| CAS DataBase Reference | 5255-17-4 |
Safety information for 3BETA-HYDROXY-DELTA5-CHOLENIC ACID
Computed Descriptors for 3BETA-HYDROXY-DELTA5-CHOLENIC ACID
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