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HomeProduct name listα-Muricholic Acid

α-Muricholic Acid

Synonym(s):5β-cholanic acid-3α,6β,7α-triol

α-Muricholic Acid Structural

What is α-Muricholic Acid?

Description

α-Muricholic acid is a murine-specific primary bile acid. Dietary administration of soybean protein decreases fecal levels of α-muricholic acid in mice with high-fat diet-induced obesity which correlates with increases in fecal Clostridium cluster XIVa, a major producer of secondary bile acids. Plasma, liver, and muscle levels of α-muricholic acid are increased in mice switched from a high-fat to low-fat diet.

The Uses of α-Muricholic Acid

α-Muricholic Acid is an bile acid found in urine. Studies have linked α-Muricholic in the understanding of the complex signaling pathways of hepatic lipid abnormalities with type 2 diabetes and a treatment target for this condition.

What are the applications of Application

5β-Cholanic acid-3α,6β,7α-triol is 5β-Cholanic acid-3α,6β,7α-triol is a cholesterol used for proteomics research.

Definition

ChEBI: Alpha-muricholic acid is a member of the class of muricholic acids in which the hydroxy groups at positions 6 and 7 have beta- and alpha- configuration respectively. It is a member of muricholic acids, a 6beta-hydroxy steroid and a 7alpha-hydroxy steroid. It is a conjugate acid of an alpha-muricholate.

Properties of α-Muricholic Acid

Melting point: 200-202 °C
Boiling point: 565.7±40.0 °C(Predicted)
Density  1.184±0.06 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 4.76±0.10(Predicted)
color  White to Off-White

Safety information for α-Muricholic Acid

Computed Descriptors for α-Muricholic Acid

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