tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate

CAS NO.：173405-78-2
Empirical Formula: C14H26N2O2
Molecular Weight: 254.37
MDL number: MFCD05861627
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-18 13:44:43

What is tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate?

Synthesis

Under argon atmosphere, wet Pd/C (188.05 mg, 159.50 μmol, purity 10%) was added into tert-butyl 9-benzyl-3,9-diazaspiro[5.5]undecane-3-carboxylate in THF solution (1.10 g, 3.19 mmol), after replacing the gas in the flask 3 times with hydrogen, the reaction was stirred at 40°C for 40 hours under 45 Psi. After completion of the reaction, the solution was filtered through diatomite. The filtrate was concentrated to give the crude tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate.

Properties of tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate

Melting point:	0°C
Boiling point:	0°C
Density	1.05
Flash point:	0°C
storage temp.	2-8°C(protect from light)
pka	11.00±0.20(Predicted)
color	White

Safety information for tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.