3,5-Dihydroxyacetophenone

CAS NO.：51863-60-6
Empirical Formula: C8H8O3
Molecular Weight: 152.15
MDL number: MFCD06656033
EINECS: 257-480-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-01 18:09:03

What is 3,5-Dihydroxyacetophenone?

Chemical properties

white to light yellow crystal powder

The Uses of 3,5-Dihydroxyacetophenone

3',5'-Dihydroxyacetophenone is a dihydroxy derivative of acetophenone. 3',5'-Dihydroxyacetophenone shows inhibitory activity towards plant germination and growth as well as some antitumor activity.

The Uses of 3,5-Dihydroxyacetophenone

3'',5''-Dihydroxyacetophenone is a dihydroxy derivative of acetophenone. 3'',5''-Dihydroxyacetophenone shows inhibitory activity towards plant germination and growth as well as some antitumor activity.

Preparation

Preparation from 3,5-dimethoxyacetophenone (SM) by demethylation with aluminium chloride in refluxing chlorobenzene (71%) The starting material (SM) was prepared by a three-step procedure from 3,5-dimethoxy-benzoic acid.

Definition

ChEBI: 3',5'-Dihydroxyacetophenone is an aromatic ketone.

Properties of 3,5-Dihydroxyacetophenone

Melting point:	145-146 °C(lit.)
Boiling point:	234.6°C (rough estimate)
Density	1.2143 (rough estimate)
refractive index	1.4447 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	8.63±0.10(Predicted)
form	Powder
color	Off-white to brown
BRN	1936502
CAS DataBase Reference	51863-60-6(CAS DataBase Reference)

Safety information for 3,5-Dihydroxyacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.