3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE

Synonym(s):3′,5-Dihydroxy-4′,6,7-trimethoxyflavone;5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one;6-Methoxyluteolin 4′,7-dimethyl ether;NSC 106402

CAS NO.：855-96-9
Empirical Formula: C18H16O7
Molecular Weight: 344.32
MDL number: MFCD00016929
EINECS: 663-133-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-07 21:39:59

3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE Structural

What is 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE?

Chemical properties

Yellow Solid

The Uses of 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE

3',5-Dihydroxy-4',6,7-trimethoxyflavone is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

The Uses of 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE

Eupatorin is a flavanoid with antiproliferative activity in cells expressing the CYP1 family. Eupatorin also displays antioxidant and anti-inflammatory activity.

Definition

ChEBI: Eupatorin is a trimethoxyflavone that is 6-hydroxyluteolin in which the phenolic hydogens at positions 4', 6 and 7 have been replaced by methyl groups. It has a role as a Brassica napus metabolite, an apoptosis inducer, a vasodilator agent, a calcium channel blocker, an anti-inflammatory agent, a P450 inhibitor and an antineoplastic agent. It is a dihydroxyflavone, a trimethoxyflavone and a polyphenol. It is functionally related to a 6-hydroxyluteolin.

Properties of 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE

Melting point:	194-196°C
Boiling point:	587.0±50.0 °C(Predicted)
Density	1.387±0.06 g/cm3(Predicted)
storage temp.	room temp
solubility	DMSO: >10mg/mL
form	powder
pka	6.31±0.40(Predicted)
color	white to beige
Water Solubility	Insoluble in water. Soluble in chloroform and methanol.
Merck	14,3901
BRN	1355109
CAS DataBase Reference	855-96-9(CAS DataBase Reference)

Safety information for 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..…