3,5-Dichlorobenzoyl chloride

Chemical properties

clear colorless to light yellow liquid or low

The Uses of 3,5-Dichlorobenzoyl chloride

3,5-Dichlorobenzoyl chloride is a useful intermediate for organic synthesis and other pharmaceutical processes.

The Uses of 3,5-Dichlorobenzoyl chloride

3,5-Dichlorobenzoyl chloride has been used in the preparation of:

• N-(1,1-dimethylpropynyl)-3,5-dichlorobenzamide, herbicide
• (3,5-dichlorophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone

Flammability and Explosibility

Non flammable

Synthesis

3,5-Dichlorobenzoyl chloride is obtained by reacting by aryl carboxylic acid with DMF.Dissolve aryl carboxylic acid (10.0 mmol) in 50 mL DCM with drops of DMF to a 100 mL roundbottomed flask. Cool the mixture to 0°C. Add oxalyl chloride (20.0 mmol, 2.0 equivalents) dropwise to the reaction mixture. Allow the reaction mixture to react for another 4 hours. Concentrate the solvent in vacuo. Use the remaining residue directly.
Fig The synthetic method of 3,5-Dichlorobenzoyl chloride