3',5'-Dibromo-4'-hydroxyacetophenone

CAS NO.：2887-72-1
Empirical Formula: C8H6Br2O2
Molecular Weight: 293.94
MDL number: MFCD00075779
EINECS: 220-750-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:37

What is 3',5'-Dibromo-4'-hydroxyacetophenone?

Preparation

Preparation by bromination of 4-hydroxyacetophenone in dilute acetic acid (94%)，(80%), (75%) (62%).

General Description

3′,5′-Dibromo-4′-hydroxyacetophenone (3,5-dibromo-4-hydroxyacetophenone) can be obtained from 4-hydroxyacetophenone, via bromination by N-bromosuccinimide in the presence of LiClO₄-SiO₂.

Properties of 3',5'-Dibromo-4'-hydroxyacetophenone

Melting point:	182-187 °C(lit.)
Boiling point:	337.7±42.0 °C(Predicted)
Density	1.936±0.06 g/cm3(Predicted)
solubility	very faint turbidity in hot Methanol
form	powder to crystal
pka	5.11±0.23(Predicted)
color	White to Almost white
CAS DataBase Reference	2887-72-1(CAS DataBase Reference)

Safety information for 3',5'-Dibromo-4'-hydroxyacetophenone

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.