3,5-DI-TERT-BUTYL-O-BENZOQUINONE

CAS NO.：3383-21-9
Empirical Formula: C14H20O2
Molecular Weight: 220.31
MDL number: MFCD00001647
EINECS: 222-189-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3,5-DI-TERT-BUTYL-O-BENZOQUINONE?

Chemical properties

dark red crystals or powder

The Uses of 3,5-DI-TERT-BUTYL-O-BENZOQUINONE

4,6-Di-tert-butyl-1,2-benzoquinone is a Ortho-Quinone derivative is know to possess a number of biological properties such as antitumoral, antimicrobacterial and anti-cardiovascular disease.

The Uses of 3,5-DI-TERT-BUTYL-O-BENZOQUINONE

3,5-Di-tert-butyl-o-benzoquinone was used in the preparation of benzoxazoles derivative ligands. It was also used in the preparation of 1,4-benzodioxines via hetero Diels Alder reaction with acyclic dienes.

Synthesis Reference(s)

Tetrahedron, 44, p. 6397, 1988 DOI: 10.1016/S0040-4020(01)89827-6
Tetrahedron Letters, 23, p. 957, 1982 DOI: 10.1016/S0040-4039(00)86993-2

General Description

Reactions of the phosphinidene-bridged complexes [Fe₂(η⁵-C₅H₅)₂(μ-PR)(μ-CO)(CO)₂] (R = Cy, Ph) with 3,5-di-tert-butyl-o-benzoquinone has been reported.

Purification Methods

It can be recrystallised from MeOH or pet ether, and forms fine red plates or rhombs. [Flaig et al. Justus Liebigs Ann Chem 597 196 1955, IR: Ley & Müller Chem Ber 89 1402 1956, Beilstein 7 IV 2113.]

Properties of 3,5-DI-TERT-BUTYL-O-BENZOQUINONE

Melting point:	112-114 °C(lit.)
Boiling point:	321.25°C (rough estimate)
Density	1.0106 (rough estimate)
refractive index	1.4970 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Very Slightly)
form	Solid
color	Very Dark Green to Very Dark Brown
BRN	2047944
Stability:	Stable. Incompatible with reducing agents, strong oxidizing agents.
CAS DataBase Reference	3383-21-9(CAS DataBase Reference)

Safety information for 3,5-DI-TERT-BUTYL-O-BENZOQUINONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.