3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL
Synonym(s):4-Methyl-2-imidazolidinethione
- CAS NO.：2055-46-1
- Empirical Formula: C4H8N2S
- Molecular Weight: 116.18
- MDL number: MFCD00060526
- EINECS: 218-152-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 13:37:16
What is 3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL?
The Uses of 3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL
Tetrahydropyrimidine-2(1H)-thione is a reactant in the preparation of aryl substituted heterocycles.
Preparation
The preparation of 3,4,5,6-Tetrahydro-2- pyrimidinethiol is as follows:Carbon disulfide (0.2 mol) was added dropwise to a solution of 1,3-diamino propane 1 (0.2 mol) in H2O/EtOH (20 ml), and the temperature was remained constant at 0-5 oC. After the completion of addition, the reaction mixture was refluxed for 12h and then cooled to room temperature. The precipitate was collected by filtration and recrystallized from EtOH to give pure desired compound.
Properties of 3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL
| Melting point: | 210-212 °C (lit.) |
| Boiling point: | 171.6±23.0 °C(Predicted) |
| Density | 1.095 (estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 14.98±0.20(Predicted) |
| form | solid |
| color | White to Off-White |
| CAS DataBase Reference | 2055-46-1(CAS DataBase Reference) |
| EPA Substance Registry System | Propylenethiourea (2055-46-1) |
Safety information for 3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![(5E)-1-ALLYL-5-[(2-METHYL-1H-INDOL-3-YL)METHYLENE]-2-THIOXODIHYDROPYRIMIDINE-4,6(1H,5H)-DIONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB3309218.gif)
![THIOPENTAL, [2-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2167813.gif)
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