3,4-DIHYDROISOQUINOLINE
- CAS NO.:3230-65-7
- Empirical Formula: C9H9N
- Molecular Weight: 131.17
- MDL number: MFCD00033714
- EINECS: 221-769-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is 3,4-DIHYDROISOQUINOLINE?
The Uses of 3,4-DIHYDROISOQUINOLINE
3,4-Dihydroisoquinoline is derived from 1,2,3,4-Tetrahydroisoquinoline (T293820), which is used as a reagent in the preparation of 4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides as antiproliferative tubulin inhibitors.
The Uses of 3,4-DIHYDROISOQUINOLINE
3,4-Dihydroisoquinoline can be used as a reactant to synthesize:
- 5,6-Dihydro-8H-isoquino[1,2-b]quinazolin-8-one by decarboxylative cyclization reaction with isatoic anhydride using tetrabutylammonium iodide (TBAI).
- 1-naphtholyl tetrahydroisoquinoline by aza-Friedel-Crafts reaction with various naphthols.
- 3,4-dihydroisoquinoline pseudo bases, which are employed as starting materials for the preperation of 3-benzazepine derivatives.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 6567, 1994 DOI: 10.1016/S0040-4039(00)78274-8
Properties of 3,4-DIHYDROISOQUINOLINE
Melting point: | 251-254℃ |
Boiling point: | 241.8±20.0℃ (760 Torr) |
Density | 1.05±0.1 g/cm3 (20 ºC 760 Torr) |
refractive index | 1.6041 (589.3 nm 30℃) |
Flash point: | 91.6±22.6℃ |
storage temp. | 2-8°C |
pka | 5.80±0.20(Predicted) |
Safety information for 3,4-DIHYDROISOQUINOLINE
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H302:Acute toxicity,oral H310:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,4-DIHYDROISOQUINOLINE
New Products
Tubulysin I Tubulysin D (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin C Diethyl Aluminium Cyanide (1.0 M in Toluene) 2,2-Difluoropropylamine hydrochloride 1-(1,1-Difluoroethyl)-2-fluorobenzene 4,4-DIFLUOROPIPERIDINE Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 4,4-DIFLUOROCYCLOHEXANAMINE 4-(Benzyloxy)-3-bromophenylacetic Acid Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Fuel shell Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
3,4-DIHYDROISOQUINOLINE
6,7-DIHYDROXY-3,4-DIHYDROISOQUINOLINE
1-METHYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE, 99+%
1-METHYL-3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE
1-(3-(6,7-DIMETHOXY(3,4-DIHYDROISOQUINOLYL))(2-PYRIDYLOXY))-4-CHLOROBENZENE
1-((6,7-DIMETHOXY(3,4-DIHYDROISOQUINOLYL))METHOXY)-2,4-DICHLOROBENZENE
6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE
You may like
-
3,4-Dihydroisoquinoline CAS 3230-65-7View Details
3230-65-7 -
(R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateView Details
2416850-45-6 -
methyl 3-fluoro-4- thiomorpholino phenylcarbamateView Details
2760359-22-4 -
Fuel shell 98%View Details
-
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
151767-02-1 Montelukast Sodium IP/USP 98%View Details
151767-02-1 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.