3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
- CAS NO.：762240-92-6
- Empirical Formula: C6H7F3N4.ClH
- Molecular Weight: 228.6
- MDL number: MFCD09817638
- EINECS: 616-309-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-02-27 17:19:27
![3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Structural](https://img.chemicalbook.in/CAS/GIF/762240-92-6.gif)
What is 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride?
Description
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is a pharmaceutical intermediate compound used in the preparation of Sitagliptin phosphate. Sitagliptin is an oral hypoglycaemic agent, a dipeptidyl peptidase-4 inhibitor, which is used in the treatment of type 2 diabetes.
Chemical properties
White Solid or White to Light yellow powder to crystal
The Uses of 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
Sitagliptin intermediate
The Uses of 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
Sitagliptin intermediate.
Properties of 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
| Melting point: | 236-246°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C6H7F3N4.ClH/c7-6(8,9)5-12-11-4-3-10-1-2-13(4)5;/h10H,1-3H2;1H |
| CAS DataBase Reference | 762240-92-6(CAS DataBase Reference) |
Safety information for 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
| InChIKey | AQCSCRYRCRORET-UHFFFAOYSA-N |
| SMILES | C12=NN=C(C(F)(F)F)N1CCNC2.[H]Cl |
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride manufacturer
Allmpus Laboratories Pvt Ltd
1Y
Phone:+91-9167862134
Whatsapp: +91-9167862134
product: Sitagliptin Triazole Hydrochloride 96.06
SETV ASRV LLP
1Y
Phone:+91-9731133411
Whatsapp: +91- 9731133411
product: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro- [1,2,4]triazolo[4,3-a]pyrazine Hydrochloride 95-99 %
OXYGENTA PHARMACEUTICAL LIMITED
1Y
Phone:+91-8712606776
product: 762240-92-6 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-triazolopyrazine Hydrochloride 99%
LOBERAN PHARMA
1Y
Phone:+91-8006595568
Whatsapp: +91- 8006595568
product: 762240-92-6 3-Trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride > 98.5
Chimerical
Gujarat
Phone:91-9265387711
Whatsapp: 91-9265387711
product: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
SRF LIMITED
Beijing
Phone:91-9650533660
Whatsapp: 91-9650533660
product: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
New Products
3-Iodophenylacetic acid 3-Pyridineacetonitrile, α-hydroxy- 2-Propanamine, 1-chloro-, hydrochloride (9CI) 3-(hexyloxy)-4-(pyridin-3-yl)-1,2,5-thiadiazole 2-Hexyn-1-ol Dibenzo-18-crown-6 Nickel(II) perchlorate hexahydrate, 98% 4-Bromophenylacetonitrile, 95% 3-Bromo-4-fluoroaniline, 97% Sodium tetraborate decahydrate, 98% Palladium(II) acetate, trimer, Pd 99% 4-Bromo-2-chlorotoluene, 97% N N Dimethylformamide Dimethyl Acetal (Dmf Dma) 2,3-Dichloro Benzoyl Cyanide [Side Chain] Bis(2-Chloroethyl) Amine Hydrochloride L-Glutamic Acid Diethyl Ester Hydrochloride 5-(Difluoromethoxy)-2-Mercaptobenzimidazole 1-Ethyl-3-(3-Dimethylaminopropyl)-Carbodiimide Hydrochloride [EDC Hcl] 1,4-Napthoquinone Bromoiodomethane Sodium Bicarbonate Methylene Dichloride (MDC) Ethyl Acetate Indole-3-Carbinol (I3C)Related products of tetrahydrofuran
You may like
-
Sitagliptin Hydrochloride 98%View Details
762240-92-6 -
Sitagliptin Triazole Hydrochloride 762240-92-6 98%View Details
762240-92-6 -
![762240-92-6 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%](https://img.chemicalbook.in//ProductImageIndia/2024-03/Raw/33a21d72-6a35-4e4a-a254-226e3127aea6.png)
762240-92-6 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%View Details
762240-92-6 -
![3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%](https://img.chemicalbook.in//ProductImageIndia/2024-03/Raw/8761a4bf-fb6d-4f58-82a7-3df786eac4e5.png)
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%View Details -
![3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%](https://img.chemicalbook.in//ProductImageIndia/2024-03/Raw/3f924c49-ad3d-42ea-bfb0-e25ab71f239a.png)
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%View Details -
![3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%](https://img.chemicalbook.in//ProductImageIndia/2024-03/Raw/f76d3ff7-1a76-4f31-88a1-33af32fafad9.png)
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 98%View Details -
Sitagliptin Impurity 20 HCl >98% (HPLC) CAS 762240-92-6View Details
762240-92-6 -
3-(Trifluoromethyl)-5,6,7,8-tetrahydro- [1,2,4]triazolo[4,3-a]pyrazine Hydrochloride 95-99 %View Details
762240-92-6
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.