3-TERT-BUTYL-4-HYDROXYANISOLE

Chemical properties

3-tert-butyl-4-hydroxyanisole is a colorless (white) crystals. Insoluble in water, soluble in alcohol, soluble at 0.05% to 0.20% in most oils. Very faint phenolic type odor.

The Uses of 3-TERT-BUTYL-4-HYDROXYANISOLE

An antioxidant stabilizer of fats that has shown carcinogenicity at high doses

The Uses of 3-TERT-BUTYL-4-HYDROXYANISOLE

antioxidant in foods (beverages, gum, ice cream, fruits, cereals), cosmetics, topical medications, animal feeds, petroleum products, jet fuels, rubber, plastics, paints, glues.

The Uses of 3-TERT-BUTYL-4-HYDROXYANISOLE

3-tert-Butyl-4-hydroxyanisole may be used as a pharmaceutical reference standard for the determination of the analyte in plasma samples using high-resolution capillary gas chromatography-mass spectrometry with selective ion monitoring.

What are the applications of Application

3-tert-Butyl-4-hydroxyanisole is an antioxidant stabilizer of fats that has shown carcinogenicity at high doses

Definition

ChEBI: 3-tert-butyl-4-hydroxyanisole is an aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group. It has a role as an antioxidant and a human xenobiotic metabolite. It is a member of phenols and an aromatic ether.

What are the applications of Application

3-tert-butyl-4-hydroxyanisole is used as an Antioxidant in foods, usually in combination with Propyl gallate and Citric acid for synergistic effect in Propylene glycol solution. Combinations with BHT (Butyl hydroxy toluene) are also used.

Preparation

from iso-Butylene and pura-Methoxyphenol.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
3-tert-Butyl-4-hydroxyanisole is a synthetic antioxidant, widely used as a food additive to prevent oxidative deterioration of fats and oils.

Flammability and Explosibility

Non flammable

Purification Methods

Fractionally distil the phenol in vacuo, then pass it as a solution in CHCl3 through alumina, and evaporate the eluate. Recrystallise the residue from pet ether. [Beilstein 6 IV 6013.]