3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID
- CAS NO.：160446-35-5
- Empirical Formula: C25H22N2O2
- Molecular Weight: 382.45
- MDL number: MFCD00237290
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID?
Chemical properties
White solid
The Uses of 3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID
3-(N-1-Trityl-imidazol-4-yl)propionic Acid is an intermediate used to prepare imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase. It is also used in the synthesis of nonracemic arylpiperazinone analogs of the carboxyl-terminal CAAL sequence of protein geranylgeranyltransferase-I (PGGTase-I) as selective inhibitors of PGGTase-I and of protein farnesyltransferase.
Properties of 3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID
| Melting point: | 185℃ (ethyl acetate tetrahydrofuran ) |
| Boiling point: | 562.8±45.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly) |
| form | Solid |
| pka | 3.94±0.10(Predicted) |
| color | White to Off-White |
Safety information for 3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID
Computed Descriptors for 3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID
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