3-(METHYLTHIO)ANILINE

Synonym(s):3-(Methylmercapto)aniline;3-Aminothioanisole

CAS NO.：1783-81-9
Empirical Formula: C7H9NS
Molecular Weight: 139.22
MDL number: MFCD00007793
EINECS: 217-232-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-26 17:21:34

What is 3-(METHYLTHIO)ANILINE?

Chemical properties

clear dark brown liquid

The Uses of 3-(METHYLTHIO)ANILINE

3-(Methylthio)aniline was used in the synthesis of phenyl azobenzene sulfonamide derivatives.

The Uses of 3-(METHYLTHIO)ANILINE

Pharmaceutical intermediate.

Hazard

See aniline.

Safety Profile

Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors ofNO_x and SO_x.

Purification Methods

Purify the aniline by fractional distillation in an inert atmostphere. It has UV max at 226 and 300nm. [Bordwell & Cooper J Am Chem Soc 74 10581952.] The N-acetyl derivative has m 78-78.5o (from aqueous EtOH). The hydrochloride has m 260-261o (aqueous EtOH/HCl) or m 225-227o (EtOH/Et2O). [Beilstein 13 H 533, 13 III 1221, 13 IV 1289.]

Properties of 3-(METHYLTHIO)ANILINE

Boiling point:	163-165 °C16 mm Hg(lit.)
Density	1.13 g/mL at 25 °C(lit.)
vapor pressure	1.66Pa at 25℃
refractive index	n20/D 1.637(lit.)
Flash point:	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	clear liquid
pka	3.96±0.10(Predicted)
Specific Gravity	1/130
color	Colorless to Light orange to Yellow
BRN	2078599
CAS DataBase Reference	1783-81-9(CAS DataBase Reference)
NIST Chemistry Reference	3-CH3SC6H4NH2(1783-81-9)
EPA Substance Registry System	m-(Methylthio)aniline (1783-81-9)

Safety information for 3-(METHYLTHIO)ANILINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.