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HomeProduct name list3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE

3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE

3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE Structural

What is 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE?

Chemical properties

Light Brown Solid

The Uses of 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE

Intermediate in the preparation of Tolcapone (T535252) and its derivatives.

The Uses of 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE

4-Hydroxy-3-methoxy-4''-methylbenzophenone is used in the preparation of Tolcapone (T535252), a selective catechol-O-methyltransferase inhibitor.

Preparation

Preparation by reaction of 33% hydrobro mic acid in acetic acid with 4-(benzyloxy)- 3-methoxy-4′-methyl-benzophenone in methylene chloride at 20–25°.

Properties of 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE

Melting point: 103–105°C
storage temp.  2-8°C
solubility  Dichloromethane
form  Solid
color  Light Brown

Safety information for 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE

Computed Descriptors for 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE

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