2-Iodo-4-methoxy-1-nitrobenzene

CAS NO.：214279-40-0
Empirical Formula: C7H6INO3
Molecular Weight: 279.03
MDL number: MFCD01320682
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-10 08:45:28

What is 2-Iodo-4-methoxy-1-nitrobenzene?

Chemical properties

yellow to orange-brown crystals or

Synthesis

Silak reaction tube equipped with a magnetic stirrer was charged with 6.2 mg of silver sulfate,21.8 mg of copper acetate, 12.5 mg of 2,9-dimethyl-1,10-o-phenanthroline,39.4 mg of 2-nitro-5-methoxybenzoic acid and 45 mg of sodium iodide4 mL of dimethyl sulfoxide. The reaction was heated at 160 ° C for 24 hours with oxygen. After the reaction, distilled water was added to quench the reaction. Extraction with ethyl acetate 3 times, each time 10mL. The combined organic phases are concentrated; 35.2 mg of 2-Iodo-4-methoxy-1-nitrobenzene was obtained in a yield of 63 percent.

Properties of 2-Iodo-4-methoxy-1-nitrobenzene

Melting point:	68-73 °C
Boiling point:	352.1±27.0 °C(Predicted)
Density	1.9259 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Crystals or Crystalline Powder
color	Yellow to orange-brown
InChI	InChI=1S/C7H6INO3/c1-12-5-2-3-7(9(10)11)6(8)4-5/h2-4H,1H3

Safety information for 2-Iodo-4-methoxy-1-nitrobenzene

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.