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HomeProduct name list3-Hydroxyphthalic anhydride

3-Hydroxyphthalic anhydride

3-Hydroxyphthalic anhydride Structural

What is 3-Hydroxyphthalic anhydride?

Chemical properties

Beige powder

The Uses of 3-Hydroxyphthalic anhydride

3-Hydroxyphthalic Anhydride is used to synthesize 3-Hydroxyphthalic Anhydride-modified human serum albumin whichhas high potency as a microbicide for prevention of the sexual transmission of HIV. It is also used as a reagent in organicsynthesis of other compounds including that of inhibitors of NF-κB derived from thalidomide.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 5092, 1955 DOI: 10.1021/ja01624a042
Synthesis, p. 788, 1985 DOI: 10.1055/s-1985-31350

Properties of 3-Hydroxyphthalic anhydride

Melting point: 199-202 °C (lit.)
Boiling point: 365.4±25.0 °C(Predicted)
Density  1.624±0.06 g/cm3(Predicted)
storage temp.  Inert atmosphere,Room Temperature
solubility  Acetonitrile (Slightly), DMSO (Slightly)
form  Powder
pka 6.25±0.20(Predicted)
color  White to beige
BRN  135783
Stability: Hygroscopic
CAS DataBase Reference 37418-88-5(CAS DataBase Reference)

Safety information for 3-Hydroxyphthalic anhydride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3-Hydroxyphthalic anhydride

InChIKey CCTOEAMRIIXGDJ-UHFFFAOYSA-N

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