2,4,6-Tribromo-3-hydroxybenzaldehyde
- CAS NO.：2737-22-6
- Empirical Formula: C7H3Br3O2
- Molecular Weight: 358.81
- MDL number: MFCD00017320
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 2,4,6-Tribromo-3-hydroxybenzaldehyde?
Description
2,4,6-Tribromo-3-hydroxybenzaldehyde (2,4,6-TBHB) is an aldehyde that is synthesized from the reaction of 2,4,6-trichlorobenzaldehyde and bromine. It has been shown to be cytotoxic in tumour cell lines in vitro. This compound binds to DNA by covalent binding and inhibits the synthesis of proteins. 2,4,6-TBHB also inhibits cellular uptake of halides such as chloride and bromide ions. This aldehyde has been shown to induce cell death in human lung cancer cells in a concentration dependent manner.
Properties of 2,4,6-Tribromo-3-hydroxybenzaldehyde
| Melting point: | 120-122°C |
| Boiling point: | 305.9±42.0 °C(Predicted) |
| Density | 2.423±0.06 g/cm3(Predicted) |
| storage temp. | Store at 0-8 ℃ |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 5.62±0.28(Predicted) |
| color | White to Almost white |
| Sensitive | Air Sensitive |
| BRN | 2098037 |
| CAS DataBase Reference | 2737-22-6(CAS DataBase Reference) |
Safety information for 2,4,6-Tribromo-3-hydroxybenzaldehyde
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2,4,6-Tribromo-3-hydroxybenzaldehyde
2,4,6-Tribromo-3-hydroxybenzaldehyde manufacturer
BASR Fine Chemicals Pvt. Ltd.
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product: 2737-22-6 98%
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