3-ETHYL-3-METHYLGLUTARIMIDE
- CAS NO.:64-65-3
- Empirical Formula: C8H13NO2
- Molecular Weight: 155.19
- MDL number: MFCD00006673
- EINECS: 200-588-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is 3-ETHYL-3-METHYLGLUTARIMIDE?
Chemical properties
white to off-white flakes or powder
The Uses of 3-ETHYL-3-METHYLGLUTARIMIDE
CNS stimulant;GABA antagonist
Definition
ChEBI: 4-ethyl-4-methylpiperidine-2,6-dione is a member of piperidones.
brand name
Megimide (Abbott).
General Description
White crystalline solid. Sublimes at 212°F and 200 mm pressure.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
3-ETHYL-3-METHYLGLUTARIMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition it emits toxic fumes.
Fire Hazard
Flash point data for 3-ETHYL-3-METHYLGLUTARIMIDE are not available. 3-ETHYL-3-METHYLGLUTARIMIDE is probably not flammable.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, intramuscular, subcutaneous, and parented routes. Human systemic effects by ingestion: wakefulness, hallucinations, distorted perceptions, toxic psychosis. An analeptic, central nervous system stimulant; used to counteract barbiturate poisoning. When heated to decomposition it emits toxic fumes of NOx.
Properties of 3-ETHYL-3-METHYLGLUTARIMIDE
Melting point: | 126-127 °C(lit.) |
Boiling point: | 279°C (rough estimate) |
Density | 1.1174 (rough estimate) |
refractive index | 1.4860 (estimate) |
storage temp. | Sealed in dry,2-8°C |
Water Solubility | Soluble in water |
solubility | DMSO:31.0(Max Conc. mg/mL);199.76(Max Conc. mM) Ethanol:31.0(Max Conc. mg/mL);199.76(Max Conc. mM) |
pka | pKa 11.7 (Uncertain) |
form | powder |
color | white |
Merck | 14,1027 |
CAS DataBase Reference | 64-65-3(CAS DataBase Reference) |
EPA Substance Registry System | Bemegride (64-65-3) |
Safety information for 3-ETHYL-3-METHYLGLUTARIMIDE
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P262:Do not get in eyes, on skin, or on clothing. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for 3-ETHYL-3-METHYLGLUTARIMIDE
New Products
Tubulysin D Tubulysin I (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride 2,2-diethoxyethanethioamide 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 4-(Benzyloxy)-3-bromophenylacetic Acid 2,2-Difluoropropylamine hydrochloride 2,2-Difluoropropanol Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- tetrahydro-4-methyl-2H-pyran 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell Calcium Sodium Phosphosilicate IH Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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